Metabolic Outcome Measures
Blood Pressure: Elevated resting blood pressure is a major risk factor for cardiovascular disease and a significant contributor to stroke. Therefore, the ability to accurately assess resting blood pressure is important to health-related research. With a BpTry BPM-200 automated blood pressure system and strict protocol, FIT can accurately measure blood pressure. FIT personnel are also able to accurately asses blood pressure manually if required.
Metabolic Analytes: Assessments of metabolic indicators of health are essential to numerous research endeavors. FIT has the capability to assess a number of metabolic health parameters both in the field and on-site. Analytes such as glucose, lipids, and HbA1C can be assess in the field or at point-of-care by utilizing validated equipment such as: the HemoCue 201, Cholestech LDX or the Afinion AS100 Analyzer. Specimens can also be collected and stored for subsequent batch analyses of a number of different analytes using a variety of UV / visible / fluorescent spectrophotometers. This range of equipment provides the flexibility to tailor outcome testing so it is specific to research goals. The list below provides examples of analytes that can be measured, but is by no means an exhaustive list. Immunoassay kits are available for a wide variety of analytes that can be quantified using existing equipment infrastructure.
Indicators of Glucose Metabolism
a. Glucose
b. HbA1C
c. Insulin
Lipid Profile
a. Total cholesterol
b. Triglycerides
c. HDL
d. LDL
Protein Assays: FIT has the ability to quantify multiple proteins specific to diabetes, metabolic syndrome, obesity, cardiovascular disease, oxidative stress and inflammation either as panels or individually.
a. Diabetes and Obesity Markers: C-peptide, Ghrelin, GIP, GLP-1, Glucagon, Insulin, Leptin, PAI-1 (total), Resistin, Visfatin, etc.
b. Inflammatory Markers: TNF superfamily of proteins, IFN family proteins, Treg cytokines, MMP’s, etc.
c. Metabolism: C-Peptide, Cortisol, Pancreatic Polypeptide, Proinsulin, Peptide YY, FSH, GH, LH and TSH